SCHEMBL927048

SCHEMBL927048

c1ccc(-c2ccc3scnc3c2)cc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK2 O43353 4/20 0.60
KDR P35968 2/20 0.60
TGFBR1 P36897 2/20 0.60
EGFR P00533 1/20 0.60
RIPK3 Q9Y572 1/20 0.57
ALDH1A1 P00352 1/20 0.55
HSD17B10 Q99714 1/20 0.55
PIK3CD O00329 1/20 0.50
FFAR1 O14842 1/20 0.49
AURKA O14965 1/20 0.46
FASN P49327 1/20 0.45
DYRK1A Q13627 1/20 0.45
ALOX5AP P20292 1/20 0.42
FEN1 P39748 1/20 0.42
MCL1 Q07820 3/20 0.42
PIK3CA P42336 1/20 0.42
PI4KA P42356 1/20 0.42
PI4KB Q9UBF8 1/20 0.42
PDE10A Q9Y233 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29478085 1.00 RIPK2 (0.60) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL28048502 0.90 ALDH1A1 (0.54) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL28215553 0.87 RIPK2 (0.50) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL10887857 0.85 RIPK2 (0.49) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL6032917 0.85 DYRK1A (0.62) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL13394464 0.83 DYRK1A (0.51) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL6650934 0.83 FFAR1 (0.48) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL1852870 0.83 FFAR1 (0.48) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL11719234 0.83 RIPK2 (0.47) RIPK2KDRTGFBR1EGFRRIPK3
SCHEMBL13394458 0.82 MAP4K4 (0.49) RIPK2KDRTGFBR1EGFRRIPK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 852 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3592729-B1 CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION STUDIENGESELLSCHAFT KOHLE MBH (DE) 2021-06-30 EP claimed
EP-0368327-B1 Light-sensitive composition FUJI PHOTO FILM CO LTD (JP) 1995-02-15 EP claimed
EP-0271260-B1 Supersensitization of silver halide emulsions MINNESOTA MINING & MFG (US) 1995-01-04 EP claimed
US-5202221-A Photocrosslinkable copolymer having maleimido side chain, cyanine dye sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US claimed
EP-0368327-A2 Light-sensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1990-05-16 EP claimed
US-4891305-A LASERS RICOH CO., LTD. (JP) 1990-01-02 US claimed
US-4889796-A CONTAINING BENZOXAZOLE COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1989-12-26 US claimed
US-4873184-A ADDITION OF A METAL COMPLEXING AGENT TO THE EMULSION; HIGH SPEED MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-10-10 US claimed
EP-0271260-A2 Supersensitization of silver halide emulsions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-06-15 EP claimed
US-3977882-A CARBOCYANINE DYES FUJI PHOTO FILM CO., LTD. (JA) 1976-08-31 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
CN-110698373-A Preparation method of N- (2- (methylthio) phenyl) acetamide compound and purification method thereof 温州大学 2020-01-17 CN disclosed
EP-1859954-B2 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2017-11-08 EP disclosed
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
EP-1975707-B1 Curable composition and planographic printing plate precursor FUJIFILM CORP (JP) 2017-07-19 EP disclosed
US-3945832-A Fogged, direct-positive silver halide emulsion containing desensitizers and a dimethine optical sensitizing dye FUJI PHOTO FILM CO., LTD. (JA) 1976-03-23 US disclosed
US-3943142-A Dye intermediates and their preparation and use in the synthesis of methine dyes EASTMAN KODAK COMPANY (US) 1976-03-09 US disclosed
US-3936308-A Photographic emulsions containing methine dyes having a 1H-imidazo[4,5-b]pyrazine nucleus EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed
US-3935010-A IMIDAZOQUINOXALINE DESENSITIZER EASTMAN KODAK COMPANY (US) 1976-01-27 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed