Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.46 |
| ▸ | KDR | P35968 | 4/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.46 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 3/20 | 0.44 |
| ▸ | FASN | P49327 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3307019 | 0.98 | DYRK1A (0.50) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| SCHEMBL28048502 | 0.88 | ALDH1A1 (0.54) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| SCHEMBL22130152 | 0.85 | DYRK1A (0.70) | DYRK1AFFAR1RIPK2TGFBR1RIPK3 | |
| SCHEMBL13394458 | 0.84 | MAP4K4 (0.49) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| SCHEMBL29363971 | 0.84 | ALDH1A1 (0.50) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| SCHEMBL115598 | 0.84 | ALDH1A1 (0.50) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| SCHEMBL927048 | 0.83 | RIPK2 (0.60) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| SCHEMBL29478085 | 0.83 | RIPK2 (0.60) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| Hydrochloric Acid SCHEMBL3303898 | 0.83 | MAP4K4 (0.47) | DYRK1AFFAR1RIPK2KDRTGFBR1 | |
| Methane SCHEMBL11806579 | 0.82 | ALDH1A1 (0.48) | DYRK1AFFAR1RIPK2KDRTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420052-B2 | Imaging agents useful for identifying AD pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-8420052-B2 | Imaging agents useful for identifying AD pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2013-04-16 | — | — | US | disclosed |
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2010-04-22 | — | — | US | disclosed |
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2010-04-22 | — | — | US | disclosed |
| WO-2010011964-A2 | IMAGING AGENTS USEFUL FOR IDENTIFYING AD PATHOLOGY | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100098634-A1 | Imaging Agents Useful for Identifying AD Pathology | APP, APBA1, PYGB | DYRK1A 3096/4885FFAR1 2289/4885RIPK2 4447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.