SCHEMBL29478393

SCHEMBL29478393

N[C@H](CC(=O)O)Cc1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 2/20 0.57
DPP4 P27487 5/20 0.49
ANPEP P15144 1/20 0.48
ENPEP Q07075 1/20 0.48
DPP8 Q6V1X1 3/20 0.47
DPP9 Q86TI2 3/20 0.47
DPP7 Q9UHL4 3/20 0.47
CTBP2 P56545 1/20 0.46
FFAR2 O15552 1/20 0.45
ALDH1A1 P00352 1/20 0.44
KMT2A Q03164 1/20 0.44
FFAR1 O14842 1/20 0.44
FOLH1 Q04609 1/20 0.44
KIF11 P52732 1/20 0.44
HTR3E A5X5Y0 2/20 0.44
HTR3B O95264 2/20 0.44
HTR3A P46098 2/20 0.44
HTR3D Q70Z44 2/20 0.44
HTR3C Q8WXA8 2/20 0.44
TAAR1 Q96RJ0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29486917 1.00 PNMT (0.57) PNMTDPP4ANPEPENPEPDPP8
SCHEMBL29478402 1.00 PNMT (0.57) PNMTDPP4ANPEPENPEPDPP8
SCHEMBL289104 1.00 PNMT (0.57) PNMTDPP4ANPEPENPEPDPP8
SCHEMBL2034385 1.00 PNMT (0.57) PNMTDPP4ANPEPENPEPDPP8
SCHEMBL1256346 1.00 PNMT (0.57) PNMTDPP4ANPEPENPEPDPP8
Hydrochloric Acid SCHEMBL1257705 0.98 PNMT (0.56) PNMTDPP4ANPEPENPEPDPP8
SCHEMBL14282773 0.86 PNMT (0.60) PNMTDPP4ANPEPENPEPDPP8
SCHEMBL288694 0.84 PNMT (0.54) PNMTDPP4ANPEPENPEPCTBP2
SCHEMBL27503089 0.84 MASP2 (0.52) PNMTCTBP2ALDH1A1KMT2AHTR3E
SCHEMBL1912600 0.84 MMEL1 (0.61) FFAR1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202010-A Ligand-oligonucleotide conjugates and linkers for use therewith 上海京新生物医药有限公司 2025-06-24 CN disclosed
CN-118879592-A Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-11-01 CN disclosed
CN-112105627-B Unnatural base pair compositions and methods of use 斯克利普斯研究所 2024-07-02 CN disclosed
CN-118139868-A Orally bioavailable nucleoside analogs 维纳拓尔斯制药公司 2024-06-04 CN disclosed
EP-4355755-A1 ORALLY-BIOAVAILABLE NUCLEOSIDE ANALOGS Venatorx Pharmaceuticals, Inc. (US) 2024-04-24 EP disclosed
WO-2024043250-A1 CYCLIC PEPTIDE OR SALT THEREOF, AND MDMX INHIBITOR 富士フイルム株式会社 2024-02-29 WO disclosed
CN-111182880-B WNT compositions and process from serum-free culture conditions 安卡萨再生疗法公司 2024-01-09 CN disclosed
EP-4228707-A1 NANOMATERIAL AND METHODS OF USE THEREOF University of Connecticut (US) 2023-08-23 EP disclosed
CN-116457034-A Nanomaterial and method of use thereof 康涅狄格大学 2023-07-18 CN disclosed
CN-116445398-A WNT composition and purification method 小利兰斯坦福大学托管委员会 2023-07-18 CN disclosed
EP-4041247-A1 EUKARYOTIC SEMI-SYNTHETIC ORGANISMS The Scripps Research Institute (US) 2022-08-17 EP disclosed
CN-114853866-A Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-08-05 CN disclosed
CN-114761026-A Compositions and methods for in vivo synthesis of non-native polypeptides 斯克利普斯研究所 2022-07-15 CN disclosed
CN-114746099-A Eukaryotic semisynthetic organisms 斯克利普斯研究所 2022-07-12 CN disclosed
CN-112500466-B Peptidomimetic macrocycles 艾瑞朗医疗公司 2022-05-03 CN disclosed
WO-2022081721-A1 NANOMATERIAL AND METHODS OF USE THEREOF UNIVERSITY OF CONNECTICUT (US) 2022-04-21 WO disclosed
CN-108348571-B Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-22 CN disclosed
CN-114206911-A Methods of treating hyperlipidemia disorders with axon-targeting factor-1 compounds 加利福尼亚大学董事会 2022-03-18 CN disclosed
CN-114207129-A Agents and methods for replication, transcription and translation in semi-synthetic organisms 斯克利普斯研究所 2022-03-18 CN disclosed
CN-114173878-A Peptidomimetic macrocycles and uses thereof 艾瑞朗医疗公司 2022-03-11 CN disclosed