SCHEMBL29480451

SCHEMBL29480451

COC(=O)[C@H](Cc1ccccc1)N(C)C(=O)[C@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSL P07711 2/20 0.45
CTSB P07858 2/20 0.45
CTSS P25774 2/20 0.45
CTSK P43235 2/20 0.45
MDM4 O15151 2/20 0.45
TP53 P04637 2/20 0.45
CASP3 P42574 1/20 0.45
OPRK1 P41145 1/20 0.44
KDM1A O60341 1/20 0.44
MAOA P21397 1/20 0.44
TNF P01375 1/20 0.44
ALDH1A1 P00352 1/20 0.43
ALOX15 P16050 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29670143 0.93 MDM4 (0.48) CTSLCTSBCTSSCTSKMDM4
SCHEMBL24414112 0.87 MMP9 (0.53) CTSLCTSBCTSSCTSKMDM4
SCHEMBL30595558 0.87 MMP9 (0.53) CTSLCTSBCTSSCTSKMDM4
SCHEMBL25412232 0.87 MMP9 (0.53) CTSLCTSBCTSSCTSKMDM4
SCHEMBL13323329 0.87 CTSL (0.47) CTSLCTSBCTSSCTSKMDM4
SCHEMBL8355963 0.87 CTSL (0.47) CTSLCTSBCTSSCTSKMDM4
SCHEMBL13743302 0.86 ATM (0.53) MDM4TP53CASP3TNFALDH1A1
SCHEMBL2977877 0.86 ATM (0.53) MDM4TP53CASP3TNFALDH1A1
SCHEMBL12531899 0.86 ATM (0.53) MDM4TP53CASP3TNFALDH1A1
SCHEMBL29401932 0.86 ATM (0.53) MDM4TP53CASP3TNFALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12528834-B2 Method for producing peptide compound NISSAN CHEMICAL CORPORATION (JP) 2026-01-20 US disclosed
US-20220372069-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND NISSAN CHEMICAL CORPORATION (JP) 2022-11-24 US disclosed
EP-4036103-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND Nissan Chemical Corporation (JP) 2022-08-03 EP disclosed
CN-114401978-A Method for producing peptide compound 日产化学株式会社 2022-04-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528834-B2 Method for producing peptide compound VIP, IAPP, NPPA CTSL 139/4885CTSB 559/4885CTSS 780/4885
US-20220372069-A1 METHOD FOR PRODUCING PEPTIDE COMPOUND VIP, NPPA, NGLY1 CTSL 325/4885CTSB 498/4885CTSS 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.