Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22716934 | 1.00 | NPSR1 (0.53) | NPSR1MAPTL3MBTL1TP53LMNA | |
| SCHEMBL13897436 | 0.82 | NPSR1 (0.59) | NPSR1MAPTL3MBTL1TP53LMNA | |
| SCHEMBL22736231 | 0.81 | NPC1 (0.41) | MEN1KMT2ASLC18A3 | |
| SCHEMBL22004077 | 0.80 | KCNH2 (0.43) | MAPTL3MBTL1TP53LMNATSHR | |
| SCHEMBL7315799 | 0.76 | L3MBTL1 (0.76) | NPSR1MAPTL3MBTL1TP53LMNA | |
| SCHEMBL7315808 | 0.76 | L3MBTL1 (0.76) | NPSR1MAPTL3MBTL1TP53LMNA | |
| SCHEMBL3595154 | 0.76 | NPSR1 (0.70) | NPSR1MAPTL3MBTL1TP53LMNA | |
| SCHEMBL29480691 | 0.75 | KMT2A (0.51) | KMT2A | |
| SCHEMBL21795781 | 0.75 | KMT2A (0.51) | KMT2A | |
| SCHEMBL22003706 | 0.75 | MEN1 (0.54) | TSHRMEN1KMT2ASLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| EP-3976612-A1 | NOVEL COMPOUNDS FOR INHIBITION OF JANUS KINASE 1 | MANKIND PHARMA LTD (IN) | 2022-04-06 | — | — | EP | disclosed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |