Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 7/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 3/20 | 0.31 |
| ▸ | JAK1 | P23458 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31158291 | 0.87 | TLR7 (0.32) | TLR7GRM4EGLN1BTK | |
| SCHEMBL22736015 | 0.81 | JAK1 (0.34) | TLR7GRM4RETEGLN1JAK1 | |
| SCHEMBL29480520 | 0.81 | JAK1 (0.34) | TLR7GRM4RETEGLN1JAK1 | |
| SCHEMBL29480746 | 0.81 | EGLN1 (0.39) | GRM4EGLN1GRM5 | |
| SCHEMBL22736270 | 0.81 | EGLN1 (0.39) | GRM4EGLN1GRM5 | |
| SCHEMBL22736529 | 0.79 | PIK3CD (0.36) | GRM4RETEGLN1JAK1JAK2 | |
| SCHEMBL22736320 | 0.69 | GRM4 (0.32) | GRM4EGLN1JAK1JAK2 | |
| SCHEMBL29567465 | 0.69 | GRM4 (0.32) | GRM4EGLN1JAK1JAK2 | |
| SCHEMBL22736126 | 0.68 | EGLN1 (0.37) | GRM4EGLN1GRM5 | |
| SCHEMBL29480720 | 0.68 | EGLN1 (0.37) | GRM4EGLN1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-114174294-A | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2022-03-11 | — | — | CN | disclosed |