Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 3/20 | 0.30 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29480740 | 0.87 | TLR7 (0.34) | TLR7EGLN1BTKGRM4 | |
| SCHEMBL22736126 | 0.84 | EGLN1 (0.37) | EGLN1GRM4 | |
| SCHEMBL29480720 | 0.84 | EGLN1 (0.37) | EGLN1GRM4 | |
| SCHEMBL22735925 | 0.82 | PIK3CD (0.34) | EGLN1 | |
| SCHEMBL29480689 | 0.81 | GRM4 (0.35) | EGLN1GRM4 | |
| SCHEMBL22735911 | 0.81 | GRM4 (0.35) | EGLN1GRM4 | |
| SCHEMBL22736015 | 0.77 | JAK1 (0.34) | TLR7EGLN1GRM4 | |
| SCHEMBL29480520 | 0.77 | JAK1 (0.34) | TLR7EGLN1GRM4 | |
| SCHEMBL22736327 | 0.76 | KCNJ1 (0.38) | GRM4 | |
| SCHEMBL29480741 | 0.76 | KCNJ1 (0.38) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | disclosed |