Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30368137 | 0.84 | CA1 (0.53) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| SCHEMBL1962462 | 0.84 | CA1 (0.53) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| SCHEMBL29480920 | 0.83 | TSHR (0.53) | F2RLMNATSHRALDH1A1HSD17B10 | |
| SCHEMBL29401587 | 0.81 | PRNP (0.44) | F2RALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL24254622 | 0.80 | FFAR1 (0.43) | F2RTSHRALDH1A1CA1CA2 | |
| SCHEMBL31582602 | 0.79 | LMNA (0.44) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| SCHEMBL851838 | 0.77 | CA1 (0.61) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| SCHEMBL10161076 | 0.75 | TSHR (0.57) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| SCHEMBL29279663 | 0.75 | TSHR (0.52) | LMNATSHRALDH1A1CFTRHSD17B10 | |
| SCHEMBL31347202 | 0.75 | TSHR (0.44) | LMNATSHRALDH1A1CFTRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174278-A | Dihydroorotate dehydrogenase inhibitors | 詹森生物科技公司 | 2022-03-11 | — | — | CN | disclosed |