Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61847 | 0.86 | CES2 (0.47) | FFAR1MEN1KMT2AHTT | |
| SCHEMBL29401587 | 0.85 | PRNP (0.44) | F2RMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5993493 | 0.83 | HPGD (0.35) | F2RMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29480975 | 0.80 | F2R (0.43) | F2RMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL29480920 | 0.77 | TSHR (0.53) | F2RMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL28884085 | 0.77 | F2R (0.43) | F2RMEN1KMT2AALDH1A1GABRA1 | |
| SCHEMBL29573780 | 0.76 | F2R (0.49) | F2RMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2360603 | 0.76 | F2R (0.49) | F2RMEN1KMT2AALDH1A1GAA | |
| SCHEMBL9901144 | 0.74 | CA1 (0.57) | FFAR1MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL10137794 | 0.74 | FFAR1 (0.45) | FFAR1MEN1KMT2AALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265083-A1 | Heterocycle CDK Inhibitors And Their Use Thereof | PRELUDE THERAPEUTICS INCORPORATED | 2023-08-24 | — | — | US | disclosed |
| US-20230265083-A1 | Heterocycle CDK Inhibitors And Their Use Thereof | PRELUDE THERAPEUTICS INCORPORATED | 2023-08-24 | — | — | US | disclosed |
| US-20230265083-A1 | Heterocycle CDK Inhibitors And Their Use Thereof | PRELUDE THERAPEUTICS INCORPORATED | 2023-08-24 | — | — | US | disclosed |
| WO-2022035799-A1 | HETEROCYCLE CDK INHIBITORS AND THEIR USE THEREOF | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-02-17 | — | — | WO | disclosed |
| WO-2022035799-A1 | HETEROCYCLE CDK INHIBITORS AND THEIR USE THEREOF | PRELUDE THERAPEUTICS INCORPORATED (US) | 2022-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265083-A1 | Heterocycle CDK Inhibitors And Their Use Thereof | CDK3, CDK8, CDK9 | FFAR1 4812/4885F2R 3909/4885MEN1 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.