Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.71 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.71 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 3/20 | 0.51 |
| ▸ | ITGB6 | P18564 | 2/20 | 0.49 |
| ▸ | ITGB8 | P26012 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22029510 | 0.89 | ITGB3 (0.85) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL22029436 | 0.89 | ITGB3 (0.85) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL22074115 | 0.87 | ITGAV (0.74) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL22029465 | 0.86 | ITGAV (0.59) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL22029493 | 0.86 | ITGAV (0.54) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22029467 | 0.81 | ITGAV (0.72) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL22074116 | 0.80 | ITGB3 (0.69) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL7953104 | 0.78 | ITGAV (0.79) | ITGAVITGB3ITGA2BITGB5ITGB6 | |
| SCHEMBL6423205 | 0.78 | ITGB3 (0.81) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL24362780 | 0.78 | ITGB3 (0.83) | ITGAVITGB3ITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3481814-B1 | TETRAHYDRONAPHTHYRIDINEPENTANAMIDE INTEGRIN ANTAGONISTS | UNIV ROCKEFELLER (US) | 2022-04-27 | — | — | EP | disclosed |