Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11133807 | 0.86 | KMT2A (0.36) | KMT2AMEN1MAPTKDM4EGLA | |
| SCHEMBL8599452 | 0.81 | MAPT (0.43) | KMT2AMEN1MAPTMAPK1TDP1 | |
| SCHEMBL8601130 | 0.76 | KDM4E (0.38) | KMT2AMEN1MAPTKDM4EGLA | |
| SCHEMBL8598680 | 0.74 | MAPT (0.38) | KMT2AMEN1MAPTKDM4EGLA | |
| SCHEMBL19952852 | 0.73 | IMPDH2 (0.41) | KMT2AMEN1MAPTTDP1HTT | |
| SCHEMBL9273537 | 0.72 | KDM4E (0.52) | KMT2AMEN1MAPTKDM4EGLA | |
| SCHEMBL8601044 | 0.69 | MAPT (0.40) | KMT2AMEN1MAPTKDM4EGLA | |
| SCHEMBL8603033 | 0.68 | CYP1A2 (0.47) | KMT2AMEN1MAPTMAPK1TDP1 | |
| SCHEMBL20291524 | 0.68 | CYP3A4 (0.61) | KMT2AMEN1MAPTKDM4EGLA | |
| SCHEMBL8567950 | 0.67 | CYP3A4 (0.47) | KMT2AMEN1MAPTKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257538-B1 | 9-ALKYLAMINO-1-NITROACRIDINE DERIVATIVES | NEW YORK MEDICAL COLLEGE (US) | 2010-09-08 | — | — | EP | claimed |