Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570733 | 0.80 | ALDH1A1 (0.46) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27504823 | 0.80 | KMT2A (0.40) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8562778 | 0.79 | RIPK1 (0.47) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8601483 | 0.78 | DHFR (0.47) | MAPTALDH1A1DHFRKMT2ASMN1; SMN2 | |
| SCHEMBL3207252 | 0.78 | RAB9A (0.47) | MAPTALDH1A1DHFRKMT2ASMN1; SMN2 | |
| SCHEMBL8603465 | 0.78 | DHFR (0.36) | MAPTALDH1A1DHFRKMT2ASMN1; SMN2 | |
| SCHEMBL8602040 | 0.77 | KMT2A (0.42) | MAPTALDH1A1DHFRKMT2ASMN1; SMN2 | |
| SCHEMBL8600823 | 0.75 | KMT2A (0.43) | MAPTALDH1A1KMT2ASMN1; SMN2POLB | |
| SCHEMBL8623968 | 0.75 | MAPT (0.37) | MAPTALDH1A1DHFRKMT2ASMN1; SMN2 | |
| SCHEMBL15648557 | 0.74 | KDM4E (0.38) | MAPTALDH1A1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |