Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL29484059

NC[C@H](N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 3/20 0.52
▸ FCER2 P06734 2/20 0.48
▸ MMP1 P03956 2/20 0.48
▸ REN P00797 2/20 0.48
▸ CTSL P07711 1/20 0.47
▸ IL1RN P18510 2/20 0.47
▸ ERAP2 Q6P179 2/20 0.47
▸ ERAP1 Q9NZ08 2/20 0.47
▸ PTPN2 P17706 1/20 0.45
▸ PTPRA P18433 1/20 0.45
▸ PTPN6 P29350 1/20 0.45
▸ PTPN11 Q06124 1/20 0.45
▸ CTSC P53634 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29484086 0.93 FCER2 (0.53) FCER2MMP1CTSLIL1RNERAP2
SCHEMBL29484083 0.93 FCER2 (0.53) FCER2MMP1CTSLIL1RNERAP2
Trifluoroacetic Acid SCHEMBL30164220 0.92 PTPN1 (0.54) PTPN1FCER2MMP1CTSC
Trifluoroacetic Acid SCHEMBL29484056 0.91 MME (0.56) —
Trifluoroacetic Acid SCHEMBL28505206 0.87 MMP2 (0.57) PTPN1CTSLIL1RNERAP2ERAP1
Trifluoroacetic Acid SCHEMBL29484051 0.86 ALDH1A1 (0.58) —
Trifluoroacetic Acid SCHEMBL28520566 0.86 MMP2 (0.56) PTPN1CTSLIL1RNERAP2ERAP1
SCHEMBL22925587 0.84 CTSC (0.60) FCER2MMP1CTSC
SCHEMBL22649189 0.84 CTSC (0.60) FCER2MMP1CTSC
SCHEMBL10049933 0.84 CTSC (0.60) FCER2MMP1CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612429-B2 Derivatives of dolaproine-dolaisoleuine peptides AGENSYS, INC. (US) 2026-04-28 — — US disclosed
US-20220204557-A1 DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES AGENSYS, INC. (US) 2022-06-30 — — US disclosed
US-11312748-B2 Derivatives of dolaproine-dolaisoleucine peptides AGENSYS, INC. (US) 2022-04-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220204557-A1 DERIVATIVES OF DOLAPROINE-DOLAISOLEUINE PEPTIDES DDOST, VIP, THPO PTPN1 4629/4885FCER2 4440/4885MMP1 4797/4885
US-12612429-B2 Derivatives of dolaproine-dolaisoleuine peptides DDOST, NGLY1, GRPR PTPN1 4560/4885FCER2 3360/4885MMP1 4362/4885
US-11312748-B2 Derivatives of dolaproine-dolaisoleucine peptides VIP, DDOST, DNPEP PTPN1 4584/4885FCER2 4752/4885MMP1 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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