Ularitide

Ularitide

SCHEMBL29484210

CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]2CCCN2C(=O)[C@H](C)NC(=O)[C@@H](N)[C@@H](C)O)CSSC[C@@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC1=O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NPR1 P16066 1/20 0.79
NPR3 P17342 1/20 0.79
RXFP4 Q8TDU9 5/20 0.61
RXFP3 Q9NSD7 5/20 0.61
INSR P06213 1/20 0.58
NPY2R P49146 7/20 0.58
MC4R P32245 1/20 0.58
MC1R Q01726 1/20 0.58
F11 P03951 2/20 0.56
KCNA3 P22001 1/20 0.56
KCNA1 Q09470 1/20 0.56
KLK7 P49862 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ularitide SCHEMBL27908491 1.00 NPR1 (0.79) NPR1NPR3RXFP4RXFP3INSR
Ularitide SCHEMBL29357163 0.94 NPR1 (0.71) NPR1NPR3RXFP4RXFP3INSR
SCHEMBL29689331 0.92 NPR1 (0.77) NPR1NPR3RXFP4RXFP3INSR
Carperitide SCHEMBL218549 0.92 NPR1 (0.94) NPR1NPR3RXFP4RXFP3INSR
Acetic Acid SCHEMBL29363649 0.90 NPR1 (0.87) NPR1NPR3INSRMC4RMC1R
SCHEMBL29376235 0.89 NPR1 (0.88) NPR1NPR3RXFP4RXFP3INSR
SCHEMBL29711548 0.88 NPR1 (0.86) NPR1NPR3RXFP4RXFP3INSR
Hydrochloric Acid SCHEMBL29495482 0.87 NPR1 (0.85) NPR1NPR3RXFP4RXFP3INSR
SCHEMBL31332082 0.85 NPR1 (0.78) NPR1NPR3MC4RMC1RF11
SCHEMBL29379928 0.84 NPR1 (0.78) NPR1NPR3INSRMC4RMC1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3805246-B1 METHOD FOR PURIFYING LONG CHAIN POLYPEPTIDE ULARITIDE HYBIO PHARMACEUTICAL CO LTD (CN) 2025-02-19 EP disclosed
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME LONGEVITY BIOTECH, INC. 2024-11-14 US disclosed
US-11312744-B2 Method for purifying long chain polypeptide Hybio Pharmaceutical Co., Ltd. (CN) 2022-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11312744-B2 Method for purifying long chain polypeptide VIP, SPPL2A, PSAP NPR1 119/4885NPR3 194/4885RXFP4 979/4885
US-20240374689-A1 HIGHLY ACTIVE POLYPEPTIDES AND METHODS OF MAKING AND USING THE SAME SCTR, GIPR, APLNR NPR1 21/4885NPR3 39/4885RXFP4 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.