Acetic Acid

Acetic Acid

SCHEMBL29363649

CC(=O)O.CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCCNC(=N)N)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CCCNC(=N)N)CSSC[C@@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC1=O

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MC4R known ✓ P32245 2/20 0.59
MC1R known ✓ Q01726 2/20 0.59
NPR1 P16066 1/20 0.87
NPR3 P17342 1/20 0.87
KCNA3 P22001 1/20 0.57
KCNA1 Q09470 1/20 0.57
F11 P03951 2/20 0.56
ALB P02768 1/20 0.56
MC3R P41968 1/20 0.54
TSLP Q969D9 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
TNFSF11 O14788 1/20 0.54
KLK7 P49862 3/20 0.53
KCNMA1 Q12791 1/20 0.53
KCNMB4 Q86W47 1/20 0.53
CTSG P08311 1/20 0.53
CSNK2A2 P19784 1/20 0.53
CSNK2B P67870 1/20 0.53
CSNK2A1 P68400 1/20 0.53
CSNK2A3 Q8NEV1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carperitide SCHEMBL218549 0.96 NPR1 (0.94) NPR1NPR3MC4RMC1RKCNA3
SCHEMBL29711548 0.95 NPR1 (0.86) NPR1NPR3MC4RMC1RKCNA3
Hydrochloric Acid SCHEMBL29495482 0.95 NPR1 (0.85) NPR1NPR3MC4RMC1RKCNA3
SCHEMBL29376235 0.94 NPR1 (0.88) NPR1NPR3MC4RMC1RF11
SCHEMBL31332082 0.94 NPR1 (0.78) NPR1NPR3MC4RMC1RKCNA3
SCHEMBL29379928 0.93 NPR1 (0.78) NPR1NPR3MC4RMC1RKCNA3
Ularitide SCHEMBL29484210 0.90 NPR1 (0.79) NPR1NPR3MC4RMC1RKCNA3
Ularitide SCHEMBL27908491 0.90 NPR1 (0.79) NPR1NPR3MC4RMC1RKCNA3
SCHEMBL29689331 0.88 NPR1 (0.77) NPR1NPR3MC4RMC1RKCNA3
Ularitide SCHEMBL29357163 0.84 NPR1 (0.71) NPR1NPR3MC4RMC1RKCNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4706683-A2 CHEWABLE FORMULATIONS Elanco Tiergesundheit AG (CH) 2026-03-11 EP disclosed
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2026-02-05 US disclosed
US-12465564-B2 Oral and nasal compositions and methods of treatment AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
US-20250339367-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES AQUESTIVE THERAPEUTICS, INC. (US) 2025-11-06 US disclosed
US-20250295587-A1 COMPLEX LIPID NANOPARTICLES ENCAPSULATING POLYPEPTIDES AND USES THEREOF SAIL BIOMEDICINES, INC. 2025-09-25 US disclosed
US-12403090-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-09-02 US disclosed
US-20250255780-A1 SYSTEM AND METHOD FOR MAKING PERSONALIZED INDIVIDUAL UNIT DOSES CONTAINING PHARMACEUTICAL ACTIVES AQUESTIVE THERAPEUTICS, INC. (US) 2025-08-14 US disclosed
US-12310922-B2 System and method for making personalized individual unit doses containing pharmaceutical actives AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-27 US disclosed
US-12296085-B2 Method for extracorporeal treatment of preeclampsia and related disorders ImMutriX Therapeutics, Inc. (US) 2025-05-13 US disclosed
US-12290597-B2 Oral film compositions and dosage forms having precise active dissolution profiles AQUESTIVE THERAPEUTICS, INC. (US) 2025-05-06 US disclosed
WO-2022187556-A1 THERAPEUTIC METHODS AND COMPOSITIONS COMPRISING MAGNETIZABLE NANOPARTICLES VRG STEM CELL SERVICES INC. (US) 2022-09-09 WO disclosed
EP-3423102-B1 COMPOSITION FOR USE IN THE TREATMENT OF PREECLAMPSIA IMMUTRIX THERAPEUTICS INC (US) 2022-09-07 EP disclosed
EP-4051235-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT Aquestive Therapeutics, Inc. (US) 2022-09-07 EP disclosed
WO-2022174113-A1 AGENTS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF HYPOXIA AND ISCHEMIA-RELATED DISORDERS MERAND PHARMACEUTICALS, INC. (US) 2022-08-18 WO disclosed
US-20220233471-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT AQUESTIVE THERAPEUTICS, INC. (US) 2022-07-28 US disclosed
WO-2022155544-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT AQUESTIVE THERAPEUTICS, INC. (US) 2022-07-21 WO disclosed
US-20220220561-A1 METHODS AND CLINICAL PROTOCOLS AND KITS PERTAINING TO MAKING AND USING THERAPEUTIC COMPOSITIONS FOR CELLULAR TREATMENT Advanced ReGen Medical Technologies, LLC 2022-07-14 US disclosed
US-20220152139-A1 PLANT MESSENGER PACKS ENCAPSULATING POLYPEPTIDES AND USES THEREOF FLAGSHIP PIONEERING INNOVATIONS VI, LLC 2022-05-19 US disclosed
WO-2022049149-A1 CHEWABLE FORMULATIONS ELANCO TIERGESUNDHEIT AG (CH) 2022-03-10 WO disclosed
WO-2022020756-A1 COMPOSITIONS AND METHODS FOR TREATING PAIN AND ANXIETY DISORDERS MANSELL JOHN (US) 2022-01-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220233471-A1 PRODRUG COMPOSITIONS AND METHODS OF TREATMENT CYP2C19, PAICS, CYP2B6 MC4R 2022/4885MC1R 3863/4885NPR1 1352/4885
US-20260034059-A1 ORAL FILM COMPOSITIONS AND DOSAGE FORMS HAVING PRECISE ACTIVE DISSOLUTION PROFILES SORD, SLC6A13, CACNA1A MC4R 4263/4885MC1R 2799/4885NPR1 4679/4885
US-12296085-B2 Method for extracorporeal treatment of preeclampsia and related disorders TEK, FLT4, PGF MC4R 3307/4885MC1R 3513/4885NPR1 1248/4885
US-20220220561-A1 METHODS AND CLINICAL PROTOCOLS AND KITS PERTAINING TO MAKING AND USING THERAPEUTIC COMPOSITIONS FOR CELLULAR TREATMENT CD47, HAVCR2, BST2 MC4R 4327/4885MC1R 3031/4885NPR1 3574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.