Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766997 | 0.82 | KMT2A (0.56) | KMT2AMEN1L3MBTL1EGFR | |
| SCHEMBL9863679 | 0.80 | LMNA (0.45) | LMNAKMT2AMEN1L3MBTL1HTT | |
| SCHEMBL11276722 | 0.79 | ELANE (0.39) | LMNAKMT2AMEN1L3MBTL1HTT | |
| SCHEMBL14445127 | 0.78 | PKM (0.47) | LMNAKMT2AMEN1L3MBTL1HTT | |
| SCHEMBL32668832 | 0.78 | PKM (0.47) | LMNAKMT2AMEN1L3MBTL1HTT | |
| Sulfuric Acid SCHEMBL29516595 | 0.78 | KMT2A (0.51) | KMT2AMEN1L3MBTL1EGFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL31199080 | 0.77 | PKM (0.46) | LMNAKMT2AMEN1L3MBTL1HTT | |
| Bromide SCHEMBL11705735 | 0.77 | KMT2A (0.50) | KMT2AMEN1HTTEGFRALDH1A1 | |
| SCHEMBL11099488 | 0.77 | LMNA (0.40) | LMNAKMT2AMEN1L3MBTL1HTT | |
| SCHEMBL13151737 | 0.77 | MEN1 (0.50) | LMNAKMT2AMEN1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110057932-B | Method for analyzing terbutaline sulfate related substances by high performance liquid chromatography | 上海旭东海普药业有限公司 | 2022-03-15 | — | — | CN | disclosed |