Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB known ✓ | P27338 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11766997 | 0.95 | KMT2A (0.56) | KMT2AMEN1MAOBEGFRNR4A2 | |
| Sulfuric Acid SCHEMBL11705657 | 0.92 | KMT2A (0.47) | KMT2AMEN1MAOBEGFRNR4A2 | |
| SCHEMBL11705297 | 0.87 | KMT2A (0.51) | KMT2AMEN1MAOBEGFRNR4A2 | |
| Bromide SCHEMBL11705735 | 0.86 | KMT2A (0.50) | KMT2AMEN1MAOBEGFRNR4A2 | |
| SCHEMBL11276722 | 0.81 | ELANE (0.39) | KMT2AMEN1MAOBL3MBTL1ALDH1A1 | |
| SCHEMBL11670421 | 0.79 | NPC1 (0.46) | KMT2AMEN1EGFRPTPN1ALDH1A1 | |
| Bromide SCHEMBL29484430 | 0.78 | LMNA (0.42) | KMT2AMEN1EGFRL3MBTL1ALDH1A1 | |
| Sulfuric Acid SCHEMBL29596794 | 0.78 | MEN1 (0.55) | KMT2AMEN1MAOBEGFRNR4A2 | |
| SCHEMBL11750101 | 0.77 | MAOB (0.56) | KMT2AMEN1MAOBNR4A2PTPN1 | |
| SCHEMBL11670418 | 0.76 | CYP19A1 (0.40) | KMT2AMEN1EGFRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111960955-B | Preparation method of terbutaline | 南京恒道医药科技股份有限公司 | 2022-05-13 | — | — | CN | disclosed |