Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 3/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25883117 | 1.00 | MMP13 (0.43) | MMP13L3MBTL1METTL3RETKDR | |
| SCHEMBL26583106 | 0.90 | MMP13 (0.41) | MMP13METTL3RETKDRCACNA1G | |
| SCHEMBL25310897 | 0.87 | PI4KA (0.47) | MMP13L3MBTL1RETKDRCACNA1G | |
| SCHEMBL25884881 | 0.87 | ROCK1 (0.46) | MMP13L3MBTL1CACNA1GCACNA1HDHODH | |
| SCHEMBL25883803 | 0.86 | MAPK14 (0.51) | L3MBTL1CACNA1GCACNA1HDHODHMEN1 | |
| SCHEMBL25883694 | 0.82 | SMN1; SMN2 (0.48) | MMP13METTL3RETRIPK1ALDH1A1 | |
| SCHEMBL29484997 | 0.81 | NR3C1 (0.46) | METTL3KLKB1KLK1HPGDALDH1A1 | |
| SCHEMBL25309990 | 0.81 | NR3C1 (0.46) | METTL3KLKB1KLK1HPGDALDH1A1 | |
| SCHEMBL26583169 | 0.79 | CCR1 (0.44) | L3MBTL1CACNA1GCACNA1HDHODHKLKB1 | |
| SCHEMBL30504872 | 0.78 | KLKB1 (0.52) | METTL3RETKDRKLKB1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215532-A1 | PROGRAMMED CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2023-07-26 | — | — | EP | disclosed |
| WO-2022057787-A1 | PROGRAMMED CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 中国科学院上海有机化学研究所 | 2022-03-24 | — | — | WO | disclosed |