Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 13/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310332 | 1.00 | KLKB1 (0.52) | KLKB1RIPK1SCDMETTL3RET | |
| SCHEMBL25884663 | 0.84 | SCD (0.43) | KLKB1RIPK1SCDMETTL3RET | |
| SCHEMBL25312468 | 0.81 | MKNK2 (0.46) | METTL3KDR | |
| SCHEMBL25882817 | 0.80 | MMP13 (0.43) | RETKDR | |
| SCHEMBL29484995 | 0.79 | KLKB1 (0.49) | KLKB1RIPK1METTL3 | |
| SCHEMBL25883660 | 0.79 | KLKB1 (0.49) | KLKB1RIPK1METTL3 | |
| SCHEMBL25883694 | 0.79 | SMN1; SMN2 (0.48) | RIPK1METTL3RET | |
| SCHEMBL25884695 | 0.79 | METTL3 (0.34) | KLKB1METTL3RETKDR | |
| SCHEMBL25309990 | 0.78 | NR3C1 (0.46) | KLKB1METTL3 | |
| SCHEMBL29484999 | 0.78 | MMP13 (0.43) | KLKB1RIPK1METTL3RETKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215532-A1 | PROGRAMMED CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2023-07-26 | — | — | EP | disclosed |