SCHEMBL253245

SCHEMBL253245

O=C(c1nc[nH]n1)c1nc[nH]n1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9663668 0.84 P2RX7 (0.30) P2RX7
SCHEMBL1608163 0.81 ALDH1A1 (0.48)
SCHEMBL3212184 0.80
SCHEMBL381885 0.80
SCHEMBL6243277 0.80
Potassium Ion SCHEMBL21373230 0.78
SCHEMBL7377426 0.78
SCHEMBL10798864 0.78 LTA4H (0.47)
SCHEMBL8692782 0.77 S1PR2 (0.35)
SCHEMBL4760562 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 452 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396303-B Gimalane-guaiane sesquiterpene dimer and preparation method and application thereof 中国科学院昆明植物研究所 2025-02-18 CN claimed
CN-118676436-A Electrolyte and lithium ion battery 深圳市豪鹏科技股份有限公司 2024-09-20 CN claimed
CN-114727912-B Cross-linked hyaluronic acid butyrate or butyrate-formate derivative and cross-linking method thereof 贝曼吉制药公司 2024-06-14 CN claimed
CN-117534654-A Method for preparing dabigatran etexilate intermediate by micro-channel method 江苏阿尔法集团盛基药业(宿迁)有限公司 2024-02-09 CN claimed
CN-117447448-A Synthesis method of dabigatran etexilate intermediate 江苏阿尔法集团盛基药业(宿迁)有限公司 2024-01-26 CN claimed
CN-116848092-A Process for preparing pyrimidine cyclohexyl glucocorticoid receptor modulators 科赛普特治疗公司 2023-10-03 CN claimed
CN-116396303-A Gimalane-guaiane sesquiterpene dimer and preparation method and application thereof 中国科学院昆明植物研究所 2023-07-07 CN claimed
CN-115304516-A Compounds with unconventional chromophores, their preparation and use 四川大学 2022-11-08 CN claimed
CN-114727912-A Cross-linked hyaluronic acid butyrate or butyrate-formate derivative and cross-linking method thereof 贝曼吉制药公司 2022-07-08 CN claimed
US-20220025432-A1 METHOD FOR FLUORESCENCE LABELING OF BIOLOGICAL MATERIALS, THERMALLY REMOVABLE FLUORESCENT LABELS FOR THIS METHOD, AND METHODS OF THEIR PREPARATION AND USE FUTURESYNTHESIS SPÓLKA Z O.O. (PL) 2022-01-27 US claimed
US-6486321-B2 EPOXIDATION; QUATERNIZATION BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-11-26 US claimed
US-20020133010-A1 Epoxidation; quaternization BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-19 US claimed
WO-2002051840-A1 METHOD FOR PRODUCING THE ANTICHOLINERGIC AGENT TIOTROPIUM BROMIDE BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-07-04 WO claimed
US-6403776-B1 TREATING ANTIBIOTIC COMPOUND WITH NUCLEOPHILE TO CLEAVE PROTECTING GROUP FROM HYDROXYL GROUP PFIZER INC. 2002-06-11 US claimed
EP-1088828-A2 Synthesis of carbamate ketolide antibiotics Pfizer Products Inc. (US) 2001-04-04 EP claimed
EP-0557408-A4 IMIDAZOLIDINONE COMPOUNDS 1993-10-27 EP claimed
EP-0557408-A1 IMIDAZOLIDINONE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1993-09-01 EP claimed
WO-1992007567-A1 IMIDAZOLIDINONE COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 1992-05-14 WO claimed
EP-0024538-B1 1,2,4-TRIAZOLYL-ENOL ETHERS, PROCESS FOR PREPARING THEM AND THEIR USE AS FUNGICIDES BAYER AG (DE) 1983-01-26 EP claimed
EP-0024538-A1 1,2,4-Triazolyl-enol ethers, process for preparing them and their use as fungicides BAYER AG (DE) 1981-03-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133010-A1 Epoxidation; quaternization TET3, HAO2, PPOX P2RX7 2362/4885
US-20220025432-A1 METHOD FOR FLUORESCENCE LABELING OF BIOLOGICAL MATERIALS, THERMALLY REMOVABLE FLUORESCENT LABELS FOR THIS METHOD, AND METHODS OF THEIR PREPARATION AND USE DUT, NOP2, NUDT1 P2RX7 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.