Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ASPH | Q12797 | 1/20 | 0.47 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4A | O75164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83616 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL27488847 | 0.98 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL28522400 | 0.86 | SMN1; SMN2 (0.46) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL6959623 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL1031057 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| Ethyl Acetate SCHEMBL28335611 | 0.82 | LMNA (0.42) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL19857453 | 0.81 | KDM4E (0.60) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL6637378 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL30961407 | 0.81 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNAKDM4CKDM5AKDM4E | |
| SCHEMBL1760077 | 0.81 | KDM4E (0.43) | SMN1; SMN2LMNAKDM4ETDP1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423741-B | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2023-11-07 | — | — | CN | disclosed |
| CN-116685584-A | N- (2, 3-dihydro-1, 4-benzoxazin-4-yl) -3-isopropyl-7- (2, 3, 5-trifluorophenyl) benzothiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections | 礼蓝动物保健有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-114423741-A | aryl-N-aryl derivatives for the treatment of RNA viral infections | ABIVAX公司 | 2022-04-29 | — | — | CN | disclosed |