Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.73 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL28058207 | 1.00 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL28070100 | 1.00 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL28121484 | 1.00 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL28134634 | 1.00 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL28223425 | 1.00 | TSHR (0.73) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL28149704 | 0.98 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL29486231 | 0.96 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL8365310 | 0.94 | TSHR (0.62) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL28097602 | 0.91 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylic Acid Methyl Ester SCHEMBL27763453 | 0.91 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3977986-A1 | ENTERIC TABLET CONTAINING DIMETHYL FUMARATE | CURACLE Co., Ltd. (KR) | 2022-04-06 | — | — | EP | disclosed |
| US-20220087942-A1 | ENTERIC TABLET CONTAINING DIMETHYL FUMARATE | CURACLE CO., LTD. (KR) | 2022-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220087942-A1 | ENTERIC TABLET CONTAINING DIMETHYL FUMARATE | SI, FH, SLC10A2 | TSHR 4434/4885HPGD 915/4885ALDH1A1 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.