Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.46 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27807398 | 0.86 | GRIA1 (0.49) | ENPP2MKNK1MKNK2MAPTGRIA1 | |
| SCHEMBL1067164 | 0.82 | LMNA (0.52) | ENPP2MKNK1MKNK2MAPTSIRT6 | |
| SCHEMBL1839319 | 0.82 | HPGD (0.51) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL20536197 | 0.82 | CYP19A1 (0.52) | ENPP2MKNK1MKNK2MAPTGRIA1 | |
| SCHEMBL17630137 | 0.82 | GRIA1 (0.46) | ENPP2MKNK1MKNK2MAPTGRIA1 | |
| SCHEMBL7470078 | 0.81 | MAPT (0.46) | ENPP2MKNK1MKNK2MAPTGRIA1 | |
| SCHEMBL6964006 | 0.79 | IDO1 (0.53) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL16151007 | 0.79 | MAPT (0.50) | ENPP2MKNK1MKNK2MAPTGRIA1 | |
| SCHEMBL10902263 | 0.79 | MAPT (0.47) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL7425462 | 0.79 | PDE2A (0.46) | ENPP2MKNK1MKNK2MAPTGRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022060943-A1 | COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |