Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.46 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.46 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067164 | 0.88 | LMNA (0.52) | MAPTLMNATDP1PDE2APDE3B | |
| SCHEMBL27807398 | 0.86 | GRIA1 (0.49) | MAPTLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10902263 | 0.82 | MAPT (0.47) | MAPTALDH1A1CYP3A4PDE3BPDE3A | |
| SCHEMBL6964006 | 0.82 | IDO1 (0.53) | MAPTLMNAGRIA1GRIA2GRIA3 | |
| SCHEMBL5036730 | 0.81 | CA1 (0.43) | MAPTLMNAPDE2APDE3BPDE3A | |
| SCHEMBL3391496 | 0.80 | MAPT (0.55) | MAPTLMNATDP1MEN1POLB | |
| SCHEMBL17630137 | 0.79 | GRIA1 (0.46) | MAPTLMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL20536197 | 0.79 | CYP19A1 (0.52) | MAPTLMNACYP3A4GRIA1GRIA2 | |
| SCHEMBL1839319 | 0.79 | HPGD (0.51) | MAPTCYP3A4PDE3BPDE3AGRIA1 | |
| SCHEMBL29486349 | 0.79 | ENPP2 (0.50) | MAPTLMNACYP3A4GRIA1GRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981533-B1 | PROTEIN KINASE INHIBITORS | ORION CORP (FI) | 2017-12-06 | — | — | EP | disclosed |
| EP-2981533-A1 | PROTEIN KINASE INHIBITORS | Orion Corporation (FI) | 2016-02-10 | — | — | EP | disclosed |
| US-20160031855-A1 | PROTEIN KINASE INHIBITORS | ORION CORPORATION (FI) | 2016-02-04 | — | — | US | disclosed |
| WO-2014162039-A1 | PROTEIN KINASE INHIBITORS | ORION CORPORATION (FI) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031855-A1 | PROTEIN KINASE INHIBITORS | FGFR1, FGFR2, FGFR3 | MAPT 3430/4885LMNA 3680/4885TDP1 2417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.