Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10432471 | 0.83 | HSD17B10 (0.49) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7367989 | 0.81 | ALDH1A1 (0.46) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6233163 | 0.78 | PNP (0.58) | GAAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9885890 | 0.77 | KMT2A (0.47) | GAAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9885887 | 0.77 | KMT2A (0.47) | GAAKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL9199287 | 0.76 | LMNA (0.40) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL515776 | 0.76 | ALDH1A1 (0.54) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9845193 | 0.75 | GAA (0.59) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL13728723 | 0.75 | GAA (0.59) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL27193125 | 0.73 | PDE4A (0.55) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4401833-A1 | GPR52 MODULATOR COMPOUNDS | Nxera Pharma UK Limited (GB) | 2024-07-24 | — | — | EP | disclosed |
| EP-4204408-A1 | GPR52 MODULATOR COMPOUNDS | Heptares Therapeutics Limited (GB) | 2023-07-05 | — | — | EP | disclosed |
| WO-2023041909-A1 | GPR52 MODULATOR COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2023-03-23 | — | — | WO | disclosed |
| WO-2022043714-A1 | GPR52 MODULATOR COMPOUNDS | HEPTARES THERAPEUTICS LIMITED (GB) | 2022-03-03 | — | — | WO | disclosed |
| CN-111467345-A | Method for inhibiting growth and metastasis of solid tumor cells and special pharmaceutical composition | 天津市人民医院 | 2020-07-31 | — | — | CN | disclosed |
| CN-110499285-A | Application of the ALPL gene in the product of preparation prevention and/or treatment low alkalinity phosphatase disease | XIAN TISSUE ENGINEERING AND REGENERATIVE MEDICINE RES INSTITUTE | 2019-11-26 | — | — | CN | disclosed |
| CN-109988746-A | A kind of mescenchymal stem cell adipogenic induction differentiation method | 上海葆年生物科技有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109714962-A | Systems and methods for culturing cells in vitro | 耶路撒冷希伯来大学的益生研究开发有限公司 | 2019-05-03 | — | — | CN | disclosed |
| CN-105343894-B | The recombination mescenchymal stem cell of efficient secretion prostaglandin E2 (PGE2) and its application | 中国人民解放军军事医学科学院基础医学研究所 | 2019-01-29 | — | — | CN | disclosed |
| CN-109182256-A | A kind of spotted maigre Preadipocyte In Vitro be separately cultured and its abductive approach | 浙江省海洋水产研究所 | 2019-01-11 | — | — | CN | disclosed |
| CN-108192856-A | A kind of method for efficiently separating and cultivating the primary melanocyte of people | 山东大学 | 2018-06-22 | — | — | CN | disclosed |
| CN-107864627-A | Include the method and composition of adhering substrate cell | 普拉里斯坦有限公司 | 2018-03-30 | — | — | CN | disclosed |
| CN-107849533-A | Use of mesenchymal stem cells for the treatment of osteoarthritis | 洪士杰 | 2018-03-27 | — | — | CN | disclosed |
| CN-104277112-B | Long-acting hypoglycemic fusion protein | 嘉和生物药业有限公司 | 2018-01-26 | — | — | CN | disclosed |
| CN-107106613-A | Composition comprising stem cell-derived exosomes for adipogenic differentiation induction, adipose tissue regeneration, skin whitening or wrinkle improvement | 胞外体干细胞株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-106754664-A | It is a kind of to induce the culture medium that break up into fat of Skeletal Muscle derived stem cells and its apply and into fat differentiation method | 广州赛莱拉干细胞科技股份有限公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106508892-A | Umbilical cord tissue cryopreservation solution and cryopreservation method | 广州赛莱拉干细胞科技股份有限公司 | 2017-03-22 | — | — | CN | disclosed |
| CN-106381283-A | Adipogenesis induction culture medium and adipogenic differentiation method | 广州赛莱拉干细胞科技股份有限公司 | 2017-02-08 | — | — | CN | disclosed |
| WO-2014205081-A1 | PHARMACEUTICAL FORMULATIONS OF XANTHINE OR XANTHINE DERIVATIVES, AND THEIR USE | IMPRIMIS PHARMACEUTICALS INC. (US) | 2014-12-24 | — | — | WO | disclosed |
| EP-1735278-B1 | HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES | LILLY CO ELI (US) | 2010-01-06 | — | — | EP | disclosed |