Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169145 | 0.87 | KDM4E (0.41) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL9199287 | 0.85 | LMNA (0.40) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL2948723 | 0.81 | GAA (0.53) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8884657 | 0.78 | PNP (0.51) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL10432471 | 0.77 | HSD17B10 (0.49) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL3141045 | 0.76 | KMT2A (0.43) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7416953 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL515776 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL7455166 | 0.71 | SMN1; SMN2 (0.61) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL23797830 | 0.69 | HTT (0.42) | ALDH1A1KDM4EHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869450-A | AMINO ACID SEQUENCES OF PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-02-09 | — | — | US | disclosed |
| WO-1997032898-A9 | ANTI-INFLAMMATORY CRF ANALOGS, THEIR COMPOSITIONS AND USE | — | 1997-10-30 | — | — | WO | disclosed |
| WO-1997032898-A1 | ANTI-INFLAMMATORY CRF ANALOGS, THEIR COMPOSITIONS AND USE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-12 | — | — | WO | disclosed |