SCHEMBL29487374

SCHEMBL29487374

C=CC(=O)OCc1c(C(=O)O)ccc(C(=O)O)c1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.41
TSHR P16473 8/20 0.35
ALDH1A1 P00352 6/20 0.35
TP53 P04637 3/20 0.35
HIF1A Q16665 3/20 0.35
CYP3A4 P08684 3/20 0.35
HSD17B10 Q99714 2/20 0.35
GAA P10253 1/20 0.34
APEX1 P27695 1/20 0.34
HCAR2 Q8TDS4 1/20 0.33
HPGD P15428 2/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
CYP1A2 P05177 1/20 0.32
LMNA P02545 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28181724 0.88 THRB (0.37) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL29597270 0.84 THRB (0.49) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL28137565 0.83 THRB (0.35) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL30698061 0.83 THRB (0.35) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL30049181 0.82 THRB (0.47) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL29487385 0.81 TSHR (0.49) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL1265100 0.81 TSHR (0.49) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL29367471 0.80 TSHR (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL30593333 0.80 TSHR (0.51) THRBTSHRALDH1A1TP53HIF1A
SCHEMBL30049822 0.80 TSHR (0.51) THRBTSHRALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US claimed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US claimed
EP-4312947-A1 SELF-ADHESIVE FISSURE SEALANT Kulzer GmbH (DE) 2024-02-07 EP claimed
WO-2022207879-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2022-10-06 WO claimed
US-12441654-B2 Porous glass nanoparticles and dentin adhesive composition comprising same MEDICLUS (KR) 2025-10-14 US disclosed
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-12-26 US disclosed
US-12173149-B2 Composite particles, kit, material, and method for producing composite particles SUN MEDICAL CO., LTD. (JP) 2024-12-24 US disclosed
EP-3666247-B1 DIVIDED CURABLE COMPOSITION MITSUI CHEMICALS INC (JP) 2024-12-18 EP disclosed
WO-2024190887-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2024-09-19 WO disclosed
WO-2024190888-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2024-09-19 WO disclosed
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2024-07-04 US disclosed
US-20240148613-A1 DENTAL POLYMERIZATION KIT SUN MEDICAL CO., LTD. (JP) 2024-05-09 US disclosed
WO-2022209944-A1 DENTAL POLYMERIZATION KIT サンメディカル株式会社 2022-10-06 WO disclosed
WO-2022207877-A1 SELF-ADHESIVE DENTAL MATERIAL KULZER GMBH (DE) 2022-10-06 WO disclosed
WO-2022207879-A1 SELF-ADHESIVE FISSURE SEALANT KULZER GMBH (DE) 2022-10-06 WO disclosed
US-20220169844-A1 COMPOSITE PARTICLES, KIT, MATERIAL, AND METHOD FOR PRODUCING COMPOSITE PARTICLES SUN MEDICAL CO., LTD. (JP) 2022-06-02 US disclosed
US-11306160-B2 Curable composition MITSUI CHEMICALS, INC. (JP) 2022-04-19 US disclosed
US-11292905-B2 Composite particles, kit, material, and method for producing composite particles SUN MEDICAL CO., LTD. (JP) 2022-04-05 US disclosed
EP-3415539-B1 POLYMERIZABLE COMPOSITION AND KIT THEREOF, AND POLYMERIZATION INITIATOR SUN MEDICAL CO LTD (JP) 2022-03-30 EP disclosed
EP-3278787-B1 POLYMERIZABLE MONOMER FOR DENTAL MATERIALS, COMPOSITION, ADHESIVE DENTAL MATERIAL, AND KIT MITSUI CHEMICALS INC (JP) 2022-03-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11306160-B2 Curable composition COIL, CLPX, CBX7 THRB 4733/4885TSHR 4794/4885ALDH1A1 1416/4885
US-20240423878-A2 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885TSHR 1186/4885ALDH1A1 318/4885
US-20240216229-A1 SELF-ADHESIVE FISSURE SEALANT ESD, GFER, FUS THRB 894/4885TSHR 1186/4885ALDH1A1 318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.