Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.40 |
| ▸ | HTR1A | P08908 | 6/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28671808 | 1.00 | HCRTR2 (0.40) | HCRTR2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28692952 | 0.83 | HTR1A (0.41) | HCRTR2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL29487573 | 0.83 | HTR1A (0.41) | HCRTR2HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23293093 | 0.83 | HCRTR2 (0.40) | HCRTR2DRD4 | |
| SCHEMBL29487560 | 0.83 | HCRTR2 (0.40) | HCRTR2DRD4 | |
| SCHEMBL23293095 | 0.83 | HCRTR2 (0.40) | HCRTR2DRD4 | |
| SCHEMBL29487583 | 0.82 | HCRTR2 (0.35) | HCRTR2LPLLIPCLIPGDRD4 | |
| SCHEMBL28675350 | 0.82 | HCRTR2 (0.35) | HCRTR2LPLLIPCLIPGDRD4 | |
| SCHEMBL30870472 | 0.81 | KDM1A (0.48) | HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24497835 | 0.81 | HCRTR2 (0.38) | HCRTR2HTR1ASLC6A2SLC6A4LPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |