Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 6/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28675350 | 1.00 | HCRTR2 (0.35) | HCRTR2IDO1LPLLIPCLIPG | |
| SCHEMBL23293095 | 0.91 | HCRTR2 (0.40) | HCRTR2DRD4 | |
| SCHEMBL29487560 | 0.91 | HCRTR2 (0.40) | HCRTR2DRD4 | |
| SCHEMBL23293093 | 0.91 | HCRTR2 (0.40) | HCRTR2DRD4 | |
| SCHEMBL23922914 | 0.85 | NR3C1 (0.38) | HCRTR2IDO1KDM4EL3MBTL1 | |
| SCHEMBL24497826 | 0.85 | NR3C1 (0.38) | HCRTR2IDO1KDM4EL3MBTL1 | |
| SCHEMBL22969642 | 0.85 | NR3C1 (0.38) | HCRTR2IDO1KDM4EL3MBTL1 | |
| SCHEMBL29487590 | 0.85 | NR3C1 (0.38) | HCRTR2IDO1KDM4EL3MBTL1 | |
| SCHEMBL29487562 | 0.82 | HCRTR2 (0.40) | HCRTR2LPLLIPCLIPGDRD4 | |
| SCHEMBL28671808 | 0.82 | HCRTR2 (0.40) | HCRTR2LPLLIPCLIPGDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181136-A | Substituted piperidine compounds and uses thereof | 武田药品工业株式会社 | 2022-03-15 | — | — | CN | disclosed |