SCHEMBL29487604

SCHEMBL29487604

COc1cncc(B2OC(C)(C)C(C)(C)O2)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SNCA P37840 1/20 0.42
LPL P06858 4/20 0.37
LIPG Q9Y5X9 4/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA9 Q16790 1/20 0.37
ROCK2 O75116 1/20 0.36
MAP4K4 O95819 1/20 0.36
PRKACA P17612 1/20 0.36
ROCK1 Q13464 1/20 0.36
DYRK1A Q13627 1/20 0.36
NTRK3 Q16288 1/20 0.36
PKN2 Q16513 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
STK17A Q9UEE5 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP11B1 P15538 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL182869 1.00 SNCA (0.42) SNCALPLLIPGCA1CA2
SCHEMBL1428004 0.85 CHRNB2 (0.33) SNCAROCK2MAP4K4PRKACAROCK1
SCHEMBL12373176 0.83 LPL (0.44) LPLLIPGCA1CA2CA9
SCHEMBL4171200 0.83 AAK1 (0.35) SNCALPLLIPGCA1CA2
SCHEMBL3430011 0.83 DGAT1 (0.36) SNCALPLLIPGCA1CA2
SCHEMBL189898 0.82 DGAT1 (0.49) SNCALPLLIPGDGAT1UCHL1
SCHEMBL31651716 0.82 AAK1 (0.36) SNCALPLLIPGCA1CA2
SCHEMBL2066788 0.82 AAK1 (0.39) LPLLIPGCA1CA2CA9
SCHEMBL112806 0.82 AAK1 (0.36) SNCALPLLIPGCA1CA2
SCHEMBL3663224 0.82 SNCA (0.48) SNCALPLLIPGCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705291-A1 IKK-ALPHA INHIBITORS Cancer Research Technology Limited (GB) 2026-03-11 EP disclosed
EP-4605089-A1 COMPOUNDS USEFUL IN MODULATING EGFR AND PI3K Mekanistic Therapeutics LLC (US) 2025-08-27 EP disclosed
WO-2025128462-A1 NOVEL THERAPEUTIC DELIVERY MOIETIES AND USES THEREOF ELI LILLY AND COMPANY (US) 2025-06-19 WO disclosed
EP-4536637-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Nico Therapeutics, Inc. (US) 2025-04-16 EP disclosed
WO-2025068452-A1 GUANFACINE DERIVATIVES AND THEIR USE IN TREATING CANCER NEGIO THERAPEUTICS (BE) 2025-04-03 WO disclosed
WO-2025003987-A1 NOVEL CARBOXAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 동화약품주식회사 2025-01-02 WO disclosed
EP-4472956-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE, COMPOSITIONS, AND METHODS OF USE Bristol-Myers Squibb Company (US) 2024-12-11 EP disclosed
EP-4469455-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
WO-2024228035-A1 IKK-ALPHA INHIBITORS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2024-11-07 WO disclosed
WO-2024206895-A1 PYRAZOLO-PYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS RECTIFY PHARMACEUTICALS, INC. (US) 2024-10-03 WO disclosed
WO-2023067322-A1 TRICYCLIC GPR65 MODULATORS Pathios Therapeutics Limited (GB) 2023-04-27 WO disclosed
WO-2023034836-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2023-03-09 WO disclosed
EP-4086259-A1 HETEROCYCLIC COMPOUNDS AS PI3K-GAMMA INHIBITORS Incyte Corporation (US) 2022-11-09 EP disclosed
CN-115054600-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-16 CN disclosed
CN-109311887-B Pyrazolo [1,5-a ] pyrimidinecarboxamide compounds and their use in the treatment of medical conditions BIAL研发投资股份有限公司 2022-09-13 CN disclosed
CN-114984003-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-02 CN disclosed
CN-109311902-B Substituted imidazo [1,2-b ] pyridazines, imidazo [1,5-b ] pyridazines, related compounds, and uses thereof BIAL研发投资股份有限公司 2022-07-15 CN disclosed
WO-2022129915-A1 PYRAZOLE DERIVATIVES AS C-ABL INHIBITORS BENEVOLENTAI BIO LIMITED (GB) 2022-06-23 WO disclosed
CN-109415321-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-06-17 CN disclosed
EP-3371190-B1 HETEROCYCLIC COMPOUNDS AS PI3K-GAMMA INHIBITORS INCYTE CORP (US) 2022-03-30 EP disclosed