Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738669 | 1.00 | MGLL (0.46) | MGLLSRD5A2CNR2ABCG2PTGS1 | |
| SCHEMBL28738679 | 0.84 | TOP2A (0.54) | TOP2ATOP2BHTTALDH1A1MEN1 | |
| SCHEMBL29488266 | 0.83 | ABCG2 (0.48) | MGLLABCG2MEN1MAPTKMT2A | |
| SCHEMBL28738683 | 0.83 | ABCG2 (0.48) | MGLLABCG2MEN1MAPTKMT2A | |
| SCHEMBL29488269 | 0.80 | MAPT (0.45) | MGLLHTTALDH1A1MAPT | |
| SCHEMBL28308601 | 0.80 | MAPT (0.45) | MGLLHTTALDH1A1MAPT | |
| SCHEMBL29488268 | 0.80 | MAPT (0.45) | MGLLHTTALDH1A1MAPT | |
| SCHEMBL29488270 | 0.79 | XDH (0.50) | KDM4ETOP2ATOP2BCES2ALDH1A1 | |
| SCHEMBL28738673 | 0.79 | XDH (0.50) | KDM4ETOP2ATOP2BCES2ALDH1A1 | |
| SCHEMBL17786457 | 0.77 | TNKS (0.53) | ABCG2KDM4EHTTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897008-B | 2-benzoyl-6-amino-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-05-03 | — | — | CN | disclosed |