Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28308709 | 1.00 | MAPT (0.46) | MAPTPOLBSMN1; SMN2BRD4MEN1 | |
| SCHEMBL29488264 | 1.00 | MAPT (0.46) | MAPTPOLBSMN1; SMN2BRD4MEN1 | |
| SCHEMBL28308718 | 0.85 | EGFR (0.53) | MAPTSMN1; SMN2BRD4KMT2AHTT | |
| SCHEMBL28738664 | 0.84 | BRD4 (0.46) | MAPTPOLBSMN1; SMN2BRD4HTT | |
| SCHEMBL28308704 | 0.80 | ATIC (0.44) | MAPTSMN1; SMN2BRD4MEN1KMT2A | |
| SCHEMBL28738663 | 0.80 | ITGB3 (0.44) | MAPTPOLBSMN1; SMN2BRD4RXFP1 | |
| SCHEMBL29488258 | 0.79 | BRD4 (0.52) | MAPTPOLBSMN1; SMN2BRD4MEN1 | |
| SCHEMBL28738687 | 0.79 | BRD4 (0.52) | MAPTPOLBSMN1; SMN2BRD4MEN1 | |
| SCHEMBL29488268 | 0.78 | MAPT (0.45) | MAPTHTTRXFP1LMNAALDH1A1 | |
| SCHEMBL29488269 | 0.78 | MAPT (0.45) | MAPTHTTRXFP1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897008-B | 2-benzoyl-6-amino-4 (3H) -quinazolinone derivative and synthesis method and application thereof | 中南大学 | 2022-05-03 | — | — | CN | disclosed |