Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28367653 | 0.84 | KMT2A (0.39) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL29488294 | 0.84 | KMT2A (0.39) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL28373098 | 0.81 | ALDH1A1 (0.39) | KMT2AALDH1A1MEN1CCR5F2 | |
| SCHEMBL20565444 | 0.75 | CCR5 (0.44) | ALDH1A1CYP1A2CCR5F2ELANE | |
| SCHEMBL13642025 | 0.75 | KDM4E (0.50) | KMT2AALDH1A1MEN1F2ELANE | |
| SCHEMBL28367568 | 0.74 | HPGD (0.36) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL3372566 | 0.73 | KDM4E (0.49) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL13419786 | 0.73 | PTGDR2 (0.50) | KMT2AALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL28686804 | 0.72 | CCR5 (0.46) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 | |
| SCHEMBL29488290 | 0.72 | CCR5 (0.46) | KMT2AALDH1A1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |