Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29488290 | 1.00 | CCR5 (0.46) | CCR5F2ELANEHTR2AHTR2C | |
| SCHEMBL20565444 | 0.83 | CCR5 (0.44) | CCR5F2ELANECYP1A2LMNA | |
| SCHEMBL28373098 | 0.78 | ALDH1A1 (0.39) | CCR5F2ELANEMEN1KMT2A | |
| SCHEMBL28367653 | 0.76 | KMT2A (0.39) | F2ELANEMEN1KMT2AKDM4E | |
| SCHEMBL29488294 | 0.76 | KMT2A (0.39) | F2ELANEMEN1KMT2AKDM4E | |
| SCHEMBL29488295 | 0.74 | RAB9A (0.51) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL13642025 | 0.72 | KDM4E (0.50) | F2ELANEMEN1KMT2AKDM4E | |
| SCHEMBL29488293 | 0.72 | KMT2A (0.39) | CCR5F2ELANEMEN1KMT2A | |
| SCHEMBL28367568 | 0.71 | HPGD (0.36) | F2ELANEMEN1KMT2AKDM4E | |
| SCHEMBL29320859 | 0.70 | CCR5 (0.49) | CCR5CYP1A2LMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | claimed |
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |
| CN-110746345-B | Synthesis method of 2- (2-amino-5-bromo-benzoyl) pyridine | 苏州永健生物医药有限公司 | 2022-03-04 | — | — | CN | disclosed |