Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305790 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL1305792 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL29525119 | 0.86 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL1306318 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL1306323 | 0.80 | KDM4E (0.47) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL5017280 | 0.79 | HRH3 (0.45) | KDM4EALDH1A1HSD17B10PREPPRMT5 | |
| SCHEMBL1305961 | 0.78 | L3MBTL1 (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| SCHEMBL1305962 | 0.78 | L3MBTL1 (0.48) | KDM4EALDH1A1HSD17B10HPGDMAPK1 | |
| Cg-200745 SCHEMBL29761007 | 0.76 | HTR1B (0.43) | KDM4EALDH1A1MAPTADAMTS4ADAMTS5 | |
| SCHEMBL1305819 | 0.76 | TDP1 (0.50) | KDM4EALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110740989-B | Pharmaceutically acceptable salts of alkylcarbamoylnaphthoxyoctenoylhydroxyamides or derivatives thereof and process for preparing the same | 晶体基因技术株式会社 | 2022-03-08 | — | — | CN | disclosed |