Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305962 | 1.00 | L3MBTL1 (0.48) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1306323 | 0.92 | KDM4E (0.47) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1306318 | 0.92 | KDM4E (0.47) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL29525119 | 0.91 | KDM4E (0.48) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1305792 | 0.91 | KDM4E (0.48) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1305790 | 0.91 | KDM4E (0.48) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1306934 | 0.87 | L3MBTL1 (0.45) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1306936 | 0.87 | L3MBTL1 (0.45) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL1305963 | 0.86 | KDM4E (0.45) | L3MBTL1NPC1ATMKDM4EALDH1A1 | |
| SCHEMBL17043090 | 0.83 | P2RX3 (0.44) | L3MBTL1NPC1ATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053435-B2 | Naphthalenyloxypropenyl derivatives having inhibitory activity against histone deacetylase and pharmaceutical composition comprising the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-11-08 | — | — | US | disclosed |