SCHEMBL29488559

SCHEMBL29488559

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nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.34
TAS2R46 P59540 2/20 0.31
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13770796 1.00 CES2 (0.34) CES2TAS2R46PTPN1
SCHEMBL12641991 1.00 CES2 (0.34) CES2TAS2R46PTPN1
SCHEMBL17634349 0.84 PTPN1 (0.42) CES2TAS2R46PTPN1
SCHEMBL6696664 0.84 PTPN1 (0.42) CES2TAS2R46PTPN1
Hydrogen Peroxide SCHEMBL5076367 0.79 CES2 (0.40) CES2TAS2R46
SCHEMBL13770795 0.79 CES2 (0.40) CES2TAS2R46
SCHEMBL13771155 0.79 CES2 (0.40) CES2TAS2R46
SCHEMBL1446617 0.79 CES2 (0.40) CES2TAS2R46
SCHEMBL12305441 0.79 CES2 (0.40) CES2TAS2R46
SCHEMBL14747987 0.79 CES2 (0.40) CES2TAS2R46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214918-A1 FUNCTIONALIZATION OF TERPENES BY SELECTIVE DEPROTONATION FOR THE SYNTHESIS OF (+)-ARTEMISININ AND RELATED COMPOUNDS UNIV TEXAS (US) 2025-07-03 US disclosed
WO-2023225681-A9 S HOPINGFUNCTIONALIZATION OF TERPENES BY SELECTIVE DEPROTONATION FOR THE SYNTHESIS OF (+)-ARTEMISININ AND RELATED COMPOUNDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYTEM (US) 2024-03-21 WO disclosed
WO-2023225681-A2 S HOPINGFUNCTIONALIZATION OF TERPENES BY SELECTIVE DEPROTONATION FOR THE SYNTHESIS OF (+)-ARTEMISININ AND RELATED COMPOUNDS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYTEM (US) 2023-11-23 WO disclosed
CN-114231655-A SNP locus linked with artemisinin content and application thereof 华智生物技术有限公司 2022-03-25 CN disclosed
CN-114214451-A SNP locus linked with artemisinin content and application thereof 华智生物技术有限公司 2022-03-22 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214918-A1 FUNCTIONALIZATION OF TERPENES BY SELECTIVE DEPROTONATION FOR THE SYNTHESIS OF (+)-ARTEMISININ AND RELATED COMPOUNDS DHPS, SQLE, CYP11B2 CES2 2460/4885TAS2R46 1871/4885PTPN1 4845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.