Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1350460 | 1.00 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL12333067 | 0.88 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL12133508 | 0.87 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL1352886 | 0.86 | DGAT1 (0.38) | DGAT1 | |
| SCHEMBL12300503 | 0.86 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL24369445 | 0.85 | DGAT1 (0.43) | DGAT1 | |
| SCHEMBL14751075 | 0.85 | DGAT1 (0.41) | DGAT1 | |
| SCHEMBL30068572 | 0.83 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL2377487 | 0.83 | DGAT1 (0.48) | DGAT1 | |
| SCHEMBL1352573 | 0.82 | DGAT1 (0.40) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12331046-B2 | CTPS1 inhibitors and uses thereof | NIMBUS CLOTHO, INC. (US) | 2025-06-17 | — | — | US | disclosed |
| EP-4232425-A1 | CTPS1 INHIBITORS AND USES THEREOF | Nimbus Clotho, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087634-A1 | CTPS1 INHIBITORS AND USES THEREOF | NIMBUS CLOTHO, INC. (US) | 2022-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12331046-B2 | CTPS1 inhibitors and uses thereof | CTPS1, CTPS2, ECHS1 | DGAT1 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.