Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CLPP | Q16740 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28253598 | 0.84 | NSD2 (0.46) | SIRT1ALDH1A1POLBGAASIGMAR1 | |
| SCHEMBL30641516 | 0.81 | LMNA (0.42) | ALDH1A1POLB | |
| SCHEMBL31202646 | 0.76 | SIRT2 (0.43) | SIRT2SIRT1CHRM5KDM4EALDH1A1 | |
| SCHEMBL28950145 | 0.75 | DHFR (0.35) | ALDH1A1HIF1A | |
| SCHEMBL30379200 | 0.72 | SIRT1 (0.44) | SIRT1KDM4EALDH1A1NPSR1SCN9A | |
| SCHEMBL31202630 | 0.72 | BRD4 (0.45) | SIRT2SIRT1KDM4EPOLBCLPP | |
| SCHEMBL28247415 | 0.71 | MAPT (0.46) | SIRT2SIRT1CHRM5ALDH1A1NPSR1 | |
| SCHEMBL28140628 | 0.71 | KDM4E (0.38) | KDM4EALDH1A1POLB | |
| SCHEMBL31202624 | 0.69 | CYP1A2 (0.42) | ALDH1A1ACHEGAADRD2SIGMAR1 | |
| SCHEMBL31415586 | 0.69 | MAPT (0.33) | KDM4EALDH1A1POLBKCNH2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118702634-A | Methylation synthesis method of heterocyclic aromatic compound | 湖州师范学院 | 2024-09-27 | — | — | CN | disclosed |
| CN-114230528-A | Novel method for preparing quinoxalinone derivative | 桂林理工大学 | 2022-03-25 | — | — | CN | disclosed |