Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 4/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL743150 | 0.80 | MAPT (0.47) | PTGS2PTGS1ALDH1A1MAPTGAA | |
| SCHEMBL9152453 | 0.79 | MAPT (0.32) | MTNR1AMTNR1BALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL5169474 | 0.74 | GABRP (0.47) | ALDH1A1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL4091414 | 0.71 | PTGS1 (0.49) | PTGS2PTGS1ALDH1A1MAPTGAA | |
| SCHEMBL10751483 | 0.71 | HSD17B1 (0.42) | ALDH1A1CYP3A4 | |
| SCHEMBL6607453 | 0.71 | GABRP (0.36) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL22423598 | 0.69 | MTNR1A (0.39) | MTNR1AMTNR1BCES2CES1NPSR1 | |
| Hydrochloric Acid SCHEMBL6639008 | 0.69 | GABRP (0.35) | ALDH1A1SMN1; SMN2MAPTLMNACYP3A4 | |
| SCHEMBL28262959 | 0.69 | HSP90AB1 (0.42) | ALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL2692610 | 0.69 | GABRP (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7754403-B2 | asymmetric bishydroxy compound having an excellent charge transporting performance as well as excellent solubility in the solvent and compatibility with the resin where no partial crystals are created at the time of film formation, and electrical properties and durability are both excellent | SHARP KABUSHIKI KAISHA (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20070207395-A1 | Electrophotoconductor and image forming apparatus | SHARP KABUSHIKI KAISHA (JP) | 2007-09-06 | — | — | US | disclosed |