Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.37 |
| ▸ | KDR | P35968 | 7/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.34 |
| ▸ | KRAS | P01116 | 4/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862575 | 1.00 | EGFR (0.37) | EGFRKDRNUDT1APPPDGFRB | |
| SCHEMBL22862694 | 0.90 | EGFR (0.39) | EGFRKDRNUDT1APPPDGFRB | |
| SCHEMBL22862653 | 0.88 | EGFR (0.44) | EGFRKDRNUDT1APPPDGFRB | |
| SCHEMBL29490224 | 0.88 | EGFR (0.44) | EGFRKDRNUDT1APPPDGFRB | |
| SCHEMBL22862686 | 0.88 | EGFR (0.50) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL29490225 | 0.88 | EGFR (0.50) | EGFRKDRPDGFRBKRASSOS1 | |
| SCHEMBL22862715 | 0.84 | LDHA (0.45) | EGFRKDR | |
| SCHEMBL29490352 | 0.84 | LDHA (0.45) | EGFRKDR | |
| SCHEMBL22862579 | 0.82 | SOS1 (0.37) | EGFRKDRSOS1 | |
| SCHEMBL22862570 | 0.82 | RAB9A (0.38) | EGFRKDRPDGFRBKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |