Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 14/20 | 0.45 |
| ▸ | LDHB | P07195 | 12/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490352 | 1.00 | LDHA (0.45) | LDHALDHBEGFRKDR | |
| SCHEMBL29490260 | 0.89 | RAB9A (0.38) | LDHALDHBEGFRKDR | |
| SCHEMBL22862570 | 0.89 | RAB9A (0.38) | LDHALDHBEGFRKDR | |
| SCHEMBL22862684 | 0.89 | EGFR (0.49) | LDHALDHBEGFRKDR | |
| SCHEMBL29490218 | 0.89 | EGFR (0.49) | LDHALDHBEGFRKDR | |
| SCHEMBL22862694 | 0.86 | EGFR (0.39) | EGFRKDR | |
| SCHEMBL29490224 | 0.84 | EGFR (0.44) | EGFRKDR | |
| SCHEMBL22862653 | 0.84 | EGFR (0.44) | EGFRKDR | |
| SCHEMBL22862575 | 0.84 | EGFR (0.37) | EGFRKDR | |
| SCHEMBL29490242 | 0.84 | EGFR (0.37) | EGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220389028-A1 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY | 2022-12-08 | — | — | US | disclosed |
| WO-2021002986-A2 | BAX INHIBITORS AND USES THEREOF | CASE WESTERN RESERVE UNIVERSITY (US) | 2021-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389028-A1 | BAX INHIBITORS AND USES THEREOF | BAX, TMBIM6, BCL2 | LDHA 1563/4885LDHB 473/4885EGFR 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.