Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DBH | P09172 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29490279 | 0.84 | SLC29A1 (0.37) | SLC29A1ATMTDP1ALDH1A1KDM4E | |
| SCHEMBL22862960 | 0.84 | SLC29A1 (0.37) | SLC29A1ATMTDP1ALDH1A1KDM4E | |
| SCHEMBL22862594 | 0.84 | MAPT (0.40) | ALDH1A1KDM4EPOLBNR1I2HTT | |
| SCHEMBL29490276 | 0.83 | NR1I2 (0.38) | SLC29A1ATMTDP1ALDH1A1POLB | |
| SCHEMBL29490207 | 0.80 | ALDH1A1 (0.36) | SLC29A1ATMTDP1ALDH1A1KDM4E | |
| SCHEMBL29490307 | 0.77 | RAD52 (0.43) | SLC29A1ATMTDP1ALDH1A1POLB | |
| SCHEMBL24704321 | 0.74 | POLB (0.36) | SLC29A1ATMTDP1ALDH1A1KDM4E | |
| SCHEMBL29490189 | 0.74 | POLB (0.36) | SLC29A1ATMTDP1ALDH1A1KDM4E | |
| SCHEMBL22862595 | 0.69 | LMNA (0.39) | ALDH1A1HTTLMNA | |
| SCHEMBL24704619 | 0.69 | ATM (0.37) | ATMTDP1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |