Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | UBE2N | P61088 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862639 | 1.00 | POLB (0.42) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL29490210 | 0.89 | POLB (0.49) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL22862547 | 0.89 | POLB (0.49) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL22862640 | 0.85 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL29490281 | 0.85 | SMN1; SMN2 (0.41) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL22862773 | 0.83 | CYP11B2 (0.38) | SMN1; SMN2LMNAHTTUBE2NMAPK1 | |
| SCHEMBL22862941 | 0.81 | CYP11B2 (0.38) | SMN1; SMN2LMNAHTTUBE2NL3MBTL1 | |
| SCHEMBL22862945 | 0.79 | RAD52 (0.38) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL22862584 | 0.78 | THRB (0.40) | POLBSMN1; SMN2LMNAHTTUBE2N | |
| SCHEMBL29490250 | 0.78 | THRB (0.40) | POLBSMN1; SMN2LMNAHTTUBE2N |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |