Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862454 | 1.00 | GAA (0.53) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL22862457 | 0.90 | GAA (0.66) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL30497269 | 0.87 | GAA (0.70) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL29490186 | 0.83 | GAA (0.45) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL22862456 | 0.83 | GAA (0.45) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL30497313 | 0.81 | GAA (0.75) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL3352200 | 0.80 | GAA (0.61) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL4293328 | 0.79 | FLT3 (0.48) | GAAHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL16602284 | 0.76 | ALDH1A1 (0.53) | GAAHPGDALDH1A1NPC1FGFR1 | |
| SCHEMBL4743122 | 0.76 | DRD2 (0.44) | GAAHSD17B10HPGDALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |