Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.52 |
| ▸ | FLT3 | P36888 | 4/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497269 | 0.89 | GAA (0.70) | GAAHSD17B10FLT3FGFR1HPGD | |
| SCHEMBL4293328 | 0.89 | FLT3 (0.48) | GAAHSD17B10FLT3FGFR1HPGD | |
| SCHEMBL30497313 | 0.87 | GAA (0.75) | GAAHSD17B10FGFR1HPGDALDH1A1 | |
| SCHEMBL3356723 | 0.85 | GAA (0.69) | GAAHSD17B10FGFR1HPGDALDH1A1 | |
| SCHEMBL3352559 | 0.83 | ALDH1A1 (0.53) | GAAHSD17B10FLT3HPGDALDH1A1 | |
| SCHEMBL14852148 | 0.83 | FLT3 (0.45) | GAAHSD17B10FLT3HPGDALDH1A1 | |
| SCHEMBL4282464 | 0.82 | CHEK2 (0.44) | GAAHSD17B10FLT3FGFR1HPGD | |
| SCHEMBL3352205 | 0.81 | PRMT5 (0.44) | GAAHSD17B10FLT3ALDH1A1DRD2 | |
| SCHEMBL15344990 | 0.80 | DRD2 (0.49) | FLT3ALDH1A1NPC1DRD2SLC6A4 | |
| SCHEMBL22862454 | 0.80 | GAA (0.53) | GAAHSD17B10FLT3FGFR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2141163-A1 | Substituted thiazolidinones, their production and utilisation as medicine | Bayer Schering Pharma AG (DE) | 2010-01-06 | — | — | EP | disclosed |