Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | LDHA | P00338 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22862580 | 1.00 | IDH1 (0.42) | IDH1MAPK14MAPTNPSR1BDKRB1 | |
| SCHEMBL22862702 | 0.83 | LDHA (0.36) | IDH1MAPK14MAPTNPSR1LDHA | |
| SCHEMBL22862672 | 0.80 | IDH1 (0.47) | IDH1MAPTBDKRB1RAB9AKMT2A | |
| SCHEMBL29490301 | 0.80 | IDH1 (0.47) | IDH1MAPTBDKRB1RAB9AKMT2A | |
| SCHEMBL29490179 | 0.78 | SMN1; SMN2 (0.36) | IDH1MAPTNPSR1NPC1PKM | |
| SCHEMBL22862676 | 0.78 | SMN1; SMN2 (0.36) | IDH1MAPTNPSR1NPC1PKM | |
| SCHEMBL22862705 | 0.76 | NUDT1 (0.39) | MAPTNPSR1NPC1PKMRAB9A | |
| SCHEMBL22862976 | 0.76 | NUDT1 (0.39) | MAPTNPSR1NPC1PKMRAB9A | |
| SCHEMBL22862634 | 0.76 | AKR1C3 (0.35) | MAPTNPSR1KMT2AVNN1 | |
| SCHEMBL38652812 | 0.76 | RPS6KB1 (0.35) | IDH1MAPK14BDKRB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976009-A2 | BAX INHIBITORS AND USES THEREOF | Case Western Reserve University (US) | 2022-04-06 | — | — | EP | disclosed |