Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAB2 | O43741 | 4/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.40 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.40 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.40 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.40 |
| ▸ | GRK6 | P43250 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | MARS1 | P56192 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.32 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.32 |
| ▸ | ADH5 | P11766 | 2/20 | 0.32 |
| ▸ | C1S | P09871 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL22608337 | 1.00 | PRKAB2 (0.40) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL22816359 | 0.94 | PRKAG1 (0.41) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL29514802 | 0.94 | PRKAG1 (0.41) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| Trifluoroacetic Acid SCHEMBL22608241 | 0.89 | DPP4 (0.37) | GRK6DPP4DPP7DHODHIKBKB | |
| Trifluoroacetic Acid SCHEMBL22608382 | 0.88 | DPP4 (0.38) | GRK6DPP4DPP7DHODHIP6K1 | |
| SCHEMBL22608339 | 0.87 | PRKAG1 (0.35) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| Trifluoroacetic Acid SCHEMBL22807386 | 0.84 | KMO (0.41) | MARS1 | |
| SCHEMBL22815871 | 0.82 | DHODH (0.39) | GRK6DHODHIKBKBIP6K1IP6K3 | |
| Trifluoroacetic Acid SCHEMBL22608708 | 0.82 | GRK6 (0.41) | GRK6C1S | |
| SCHEMBL22815613 | 0.81 | NPC1 (0.38) | GRK6DHODHIP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3986863-A1 | GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE | BioMarin Pharmaceutical Inc. (US) | 2022-04-27 | — | — | EP | disclosed |