SCHEMBL29490993

SCHEMBL29490993

Cn1nc(I)c2c(F)cc(Br)cc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ ADORA2A P29274 1/20 0.32
▸ ADORA2B P29275 1/20 0.32
▸ NMT1 P30419 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25429967 1.00 L3MBTL1 (0.33) L3MBTL1ADORA2AADORA2BNMT1
SCHEMBL2143901 0.82 ADORA2A (0.47) L3MBTL1ADORA2AADORA2BNMT1
SCHEMBL31559591 0.82 ADORA2A (0.47) L3MBTL1ADORA2AADORA2BNMT1
SCHEMBL27170063 0.81 ADORA2A (0.37) ADORA2AADORA2B
SCHEMBL29985301 0.81 ADORA2A (0.37) ADORA2AADORA2B
SCHEMBL30791764 0.79 NMT1 (0.37) ADORA2AADORA2BNMT1
SCHEMBL24252947 0.79 NMT1 (0.37) ADORA2AADORA2BNMT1
SCHEMBL31393091 0.79 LMNA (0.34) ADORA2AADORA2B
SCHEMBL26123446 0.78 CYP11B1 (0.34) —
SCHEMBL20520461 0.74 PDK1 (0.36) L3MBTL1NMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055363-A Compounds and methods for modulating splicing 雷密克斯医疗公司 2026-05-15 — — CN disclosed
EP-4724438-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING Remix Therapeutics Inc. (US) 2026-04-15 — — EP disclosed
WO-2024259015-A1 COMPOUNDS AND METHODS FOR MODULATING SPLICING REMIX THERAPEUTICS INC. (US) 2024-12-19 — — WO disclosed
EP-4221703-A1 HSD17B13 INHIBITORS AND USES THEREOF FL2022-001, Inc. (US) 2023-08-09 — — EP disclosed
WO-2022072517-A1 HSD17B13 INHIBITORS AND USES THEREOF METACRINE, INC. (US) 2022-04-07 — — WO disclosed
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