SCHEMBL29494124

SCHEMBL29494124

CN(C(=N)N)C1CN(C2CCCCC2)C1

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.33
FAAH O00519 1/20 0.32
PHGDH O43175 1/20 0.32
MGLL Q99685 1/20 0.32
HRH3 Q9Y5N1 4/20 0.31
KCNH2 Q12809 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
XBP1 P17861 1/20 0.30
MAPK1 P28482 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
DPP4 P27487 1/20 0.30
NOS2 P35228 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4104471 0.78 FAAH (0.48) FAAHPHGDHMGLLATMNOS2
SCHEMBL10431258 0.76 FAAH (0.45) FAAHPHGDHMGLLATMNOS2
SCHEMBL4092988 0.76 FAAH (0.45) FAAHPHGDHMGLLATMNOS2
Hydrochloric Acid SCHEMBL31256658 0.69
SCHEMBL26823966 0.68 L3MBTL3 (0.34) HRH3KCNH2
SCHEMBL22602112 0.67
SCHEMBL12568612 0.66 DPP4 (0.40) HRH3KCNH2DPP4
SCHEMBL13874912 0.66 DPP4 (0.40) HRH3KCNH2DPP4
SCHEMBL16187050 0.66 ALDH1A1 (0.38) KMT2A
SCHEMBL9927929 0.66 DPP4 (0.40) HRH3KCNH2DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250197527-A1 STABLE HETERODIMERIC ANTIBODY DESIGN WITH MUTATIONS IN THE Fc DOMAIN ZYMEWORKS BC INC. (CA) 2025-06-19 US disclosed
EP-4519525-A1 LATCHING MECHANISM FOR A MOVEABLE PANEL Fort Noxs B.V. (NL) 2025-03-12 EP disclosed
US-20250034251-A1 ANTIBODY CHEMICALLY INDUCED DIMERIZER (ABCID) AS MOLECULAR SWITCHES FOR REGULATING CELLULAR THERAPIES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2025-01-30 US disclosed
US-11939379-B2 Antibody chemically induced dimerizer (AbCID) as molecular switches for regulating cellular therapies THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-26 US disclosed
WO-2023213819-A1 LATCHING MECHANISM FOR A MOVEABLE PANEL FORT NOXS B.V. (NL) 2023-11-09 WO disclosed
EP-3460095-B1 SLIDING MEMBER KK RIKEN (JP) 2022-03-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250034251-A1 ANTIBODY CHEMICALLY INDUCED DIMERIZER (ABCID) AS MOLECULAR SWITCHES FOR REGULATING CELLULAR THERAPIES BID, BAD, BCL2L10 OPRM1 4590/4885FAAH 2393/4885PHGDH 4431/4885
US-11939379-B2 Antibody chemically induced dimerizer (AbCID) as molecular switches for regulating cellular therapies BID, BAD, BCL2L10 OPRM1 4590/4885FAAH 2393/4885PHGDH 4431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.